Bronchiectasis is a chronic lung condition in which the airways (bronchi) become permanently widened and scarred. This structural damage impairs the lungs' natural ability to clear mucus, creating a cycle of mucus buildup, recurrent bacterial infections, and progressive airway inflammation.

For many patients, standard treatments — including antibiotics, airway clearance techniques, and inhaled therapies — provide incomplete relief. Exacerbations (flare-ups) remain frequent, impacting daily life, work, and overall health. This is why clinical research into new treatment approaches is critical.

Non-cystic fibrosis bronchiectasis (NCFBE) affects an estimated 500,000 adults in the United States, with prevalence increasing as diagnostic imaging improves. South Florida's warm, humid climate can exacerbate symptoms for many patients, making access to advanced treatments particularly important in our region.

The Bronchiectasis Vicious Cycle

• 1. Airway Damage — Widened, scarred bronchial tubes
• 2. Impaired Clearance — Mucus accumulates in damaged airways
• 3. Bacterial Colonization — Infections take hold (e.g., Pseudomonas)
• 4. Chronic Inflammation — Immune response damages airways further
• 5. Repeat — The cycle worsens without intervention

Clinical trials target specific steps in this cycle — breaking it with precision therapies rather than broad-spectrum antibiotics alone.

1. Free Screening Consultation

Your journey begins with a no-cost eligibility assessment. Our research coordinators review your medical history, current medications, and bronchiectasis severity to determine which study may be the best fit. This includes pulmonary function testing and review of prior CT imaging.

2. Comprehensive Baseline Evaluation

If you meet initial criteria, a thorough baseline evaluation is performed — including spirometry, laboratory tests, sputum cultures, and possibly imaging. This establishes your starting point and helps the research team monitor your progress throughout the study.

3. Treatment and Monitoring

You receive the investigational treatment at scheduled clinic visits, with regular monitoring of lung function, symptoms, infection status, and overall health. Our team is available between visits for any questions or concerns. You continue your standard bronchiectasis medications as directed.

4. Expert Specialist Care

Throughout the study, you receive care from Dr. Frank Hull and his team — board-certified pulmonary specialists with over 20 years of respiratory research experience. This level of specialist attention, comprehensive testing, and monitoring is a significant benefit of trial participation.

South Florida presents unique challenges and opportunities for bronchiectasis patients. The region's warm, humid climate supports bacterial growth and can worsen airway infections, while exposure to tropical allergens and molds may trigger additional inflammation. For many patients in Broward County, Miami-Dade, and Palm Beach, managing bronchiectasis requires more than standard treatments can offer.

Lung Research Florida, located in Plantation, FL, provides convenient access to bronchiectasis research for patients across South Florida. Our location is easily accessible from Fort Lauderdale, Sunrise, Davie, Weston, Coral Springs, and surrounding communities. We are a dedicated research facility affiliated with the Advanced Asthma Clinic, bringing decades of pulmonary expertise to every study we conduct.

As one of the few research sites in South Florida actively enrolling bronchiectasis clinical trials, we offer patients the opportunity to access investigational treatments that are not yet available through standard prescriptions — at no cost, with compensation for time and travel.

Serving Patients From:

• Plantation, FL
• Fort Lauderdale
• Sunrise & Davie
• Weston & Pembroke Pines
• Coral Springs & Parkland
• Hollywood & Hallandale Beach
• Miami-Dade County
• Palm Beach County